Effect of combined feeding of various doses of honey and black caraway oil on some biochemical and haematological parameters in normal healthy rats

Abstract

Both Black caraway oil and Honey feeding have shown some favorable effects on some biochemical parameters experimentally and these substances have been use as medicinal remedies in treatment of various diseases. Objective: This study is design to determine the effect of combined feeding of various doses of Black caraway oil and honey on some biochemical and haematological parameters in normal healthy white albino rats Methods: Thirty albino rats of Wister strain were separated in groups and fed growers mesh. In addition, the tests groups were administered various doses of honey and black caraway oil either alone or in combination into the stomach directly, through gastric intubations. Group I served as normal control fed un only growers mesh and water, while groups II and III serve as black caraway oil and honey controls to which in addition to the growers mesh and water were also given 920mg and 1420mg of black caraway oil and honey and black caraway oil. Results: Both the Black caraway oil and honey controls showed some degree of hypoglycaemia and Hypocholesterolaemia with insignificant increase in plasta triglycerides and albumin. But no effect on the other parameters when compared with normal control. However, the combine back caraway oil combined and honey fed showed significant decrease in plasma total cholesterol and increase in serum glucose and triglycerides with insignificant decreased in total protein and albumin. No changed in UREA, sodium, potassium as well as no significant change in all the hematological parameters were noticed among the groups. Conclusion: The combined feedings have hypocholesterolaemic. hyperglycerdaemic effects with insignificant hypoproteinaemic effect. It has no the renal as well as haematological systems.