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Keywords:
Anacardium occidentale ethanol extract hypoglycemic activity diabetes mellitus rats.
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The copyright of a submitted article is only transferred to the publishers if and when the article is accepted for publication. All rights reserved. No part of this publication may be reproduced, stored in a retrieval system or transmitted in any form or by any means, electronic, electrostatic, mechanical, photocopying, recording or otherwise without the prior written permission of the publishers.
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Antidiabetic activity of anacardium occidentale in alloxan – diabetic rats
Abstract
This study investigated the hypoglycemic effect of inner bark extract of Anacardium occidentale Linn. (Anacardiceae) in normal (normoglycemic) and in alloxan-induced diabetic rats. The inner reddish bark of the plant was extracted with ethanol and screened for hypoglycemic activity
in a model of alloxan-induced diabetes in at species. Bioactivity-guided fractionation of the ethanolic extract led to fractions that displayed diverse hypoglycemic effects at doses of 34.0, 200.0 and 300.0 mg/kg body weight. The alloxan-diabetic rats showed significant reduction in plasma glucose level after treatment with the fractions. These results lend support to the validity
of the folkloric use of A. occidentale in the treatment of diabetes mellitus type II.
in a model of alloxan-induced diabetes in at species. Bioactivity-guided fractionation of the ethanolic extract led to fractions that displayed diverse hypoglycemic effects at doses of 34.0, 200.0 and 300.0 mg/kg body weight. The alloxan-diabetic rats showed significant reduction in plasma glucose level after treatment with the fractions. These results lend support to the validity
of the folkloric use of A. occidentale in the treatment of diabetes mellitus type II.
