Article Sidebar
Article Details
Issue
Section
Articles
Copyright of the journal's content belongs to Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
The copyright of a submitted article is only transferred to the publishers if and when the article is accepted for publication. All rights reserved. No part of this publication may be reproduced, stored in a retrieval system or transmitted in any form or by any means, electronic, electrostatic, mechanical, photocopying, recording or otherwise without the prior written permission of the publishers.
The copyright of a submitted article is only transferred to the publishers if and when the article is accepted for publication. All rights reserved. No part of this publication may be reproduced, stored in a retrieval system or transmitted in any form or by any means, electronic, electrostatic, mechanical, photocopying, recording or otherwise without the prior written permission of the publishers.
Main Article Content
RP-LC Determination of Ascorbic Acid, Paracetamol and Caffeine in Multicomponent Anti-Cold Preparation
Abstract
An RP-LC method for the simultaneous determination of ascorbic acid paracetamol and caffeine in a tablet matrix is described. The mobile phase was a mixture of methanol-NaH, (17:83 pH 4.25 ±0.03) and stationary phase Aquapore RP-300. Total chromatographic time was approximately 8 minutes and the method found to be cost effective. The method was used to analyze some brands of multi-component anti cold preparations on the local market Results were validated using the standard UV spectrophotometric methods for the assay of the individual components of these drugs.
