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Published:
Dec 7, 2000Keywords:
Annonaceae Sesquiterpenes Flavonoids Alkaloids Anemia Salina Cytotoxicity
Article Details
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Articles
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The copyright of a submitted article is only transferred to the publishers if and when the article is accepted for publication. All rights reserved. No part of this publication may be reproduced, stored in a retrieval system or transmitted in any form or by any means, electronic, electrostatic, mechanical, photocopying, recording or otherwise without the prior written permission of the publishers.
Main Article Content
Bioactive Sesquiter Penes, Alkaloids and Flavonoids from three Annonaceous Species
Abstract
The steam back extracts of three species of the Annonaceous family namely Friesodielsia enghiana, Aratabotrys stenopetalus and Uvaria mocoli showed toxicity to the brine shrimp Aretimia salina. Series of chromatographic fractionations led to the isolation of a wide range of chemically diverse compounds including sesquiterpenes, alkaloid and flavonbids. 25 of these compound showed various degree of toxicity to the brine shrimp, over 80% showing LC50 < 100 µg/ml.
