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The copyright of a submitted article is only transferred to the publishers if and when the article is accepted for publication. All rights reserved. No part of this publication may be reproduced, stored in a retrieval system or transmitted in any form or by any means, electronic, electrostatic, mechanical, photocopying, recording or otherwise without the prior written permission of the publishers.
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Formulation of Sustained Release Theophylline Tablets using Mijcuna Gum as a Hydrophilic Retardant
Abstract
Sustained-release theophylline tablets were prepared using mucuna gum as a hydrophilic polymer. The gum was found to prolong drug release from the product.
The release rate was dependent on the gelation rate with resultant dissolution and diffusion of the active ingredient as was observed from the dissolution and liquid penetration tests carried out. The release rate was dependent on the concentration of the gum in the tablets.
