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Published:
Apr 19, 1994Keywords:
Griffonin Red Blood Cell Sickle-Cell Anemia Hemoglobin Deoxyhaemoglobin Antisickling
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The copyright of a submitted article is only transferred to the publishers if and when the article is accepted for publication. All rights reserved. No part of this publication may be reproduced, stored in a retrieval system or transmitted in any form or by any means, electronic, electrostatic, mechanical, photocopying, recording or otherwise without the prior written permission of the publishers.
Main Article Content
Studies on Antisickling Effects of Griffonin
Abstract
Results obtained from in vitro hematological studies show that griffonin causes sickled red blood cells to revert to the normal shape. The antisickling effect of griffonin was dose-and time-dependent. There was no difference between the antisickling effect of griffonin on red blood cells containing the various types Otabuormal hemoglobin, namely, hemoglobin SS SC. On weight basis' griffonin was, more potent antisickling agent than urea.
