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Published:
Apr 16, 1993Keywords:
Gamma-piperazinyl alcohols Phase-Transfer Catalyzed (PTC) Esterification Procedures Solid-Liquid PTC Conditions
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The copyright of a submitted article is only transferred to the publishers if and when the article is accepted for publication. All rights reserved. No part of this publication may be reproduced, stored in a retrieval system or transmitted in any form or by any means, electronic, electrostatic, mechanical, photocopying, recording or otherwise without the prior written permission of the publishers.
Main Article Content
Application of Phase-Transfer Catalysis in the Synthesis of Esters of Some Spasmolytically Active Gamapiperaziny Proponols
Abstract
The principles of phase-transfer catalysis was applied for the synthesis of some Gamma-piperazinyl propanols of general formula 1, which were synthesized for the purpose of studying the influence of esterification on their spasmolytic activity. It was found out that, esters of this type can be obtained in very good yields, utilizing the solid-liquid phase-transfer catalyzed (PTC) conditions and not the liquid-liquid PTC conditions. The method and conditions for their successful syntheses are described in this paper.
