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DOI:
10.4314/jpb.v8i1.8Keywords:
Mean survival time PCV Casuarina equistifolia Mangifera indica Plasmodium berghei
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Main Article Content
Effects of Mangifera indica and Casuarina equistifolia extracts on survival and haematocrit of Plasmodium berghei infected mice
Abstract
The mean survival time (mst) and haematocrit was determined following treatment of Plasmodium berghei infected mice with Casuarina equistifolia and Mangifera indica (leaf) extracts during established infection and repository test procedures. The survival time was significant (P<0.05) and dose dependent compared to the control group. The packed cell volume (PCV) taken on day zero and seven following established infection indicated that both extracts failed significantly (P<0.0.5) in preventing reduction of PCV in infected mice although some what lesser percentages where observed in 400 and 200mg/kg C. equistifolia. In the repository test, significant drop in PCV (P<0.05) was observed in all the groups except the chloroquine phosphate group.
