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Main Article Content
Isolation and characterisation of cupressuflavone from the leaves of Lophira lanceolata
Abstract
The leaf of Lophira lanceolata (Ochnaceae) is used by traditional medicine practitioners in Africa and other parts of the world to treat dysentery. Preliminary phytochemical examination of the extracts of the leaves of Lophira lanceolata indicated the presence of flavonoids, anthraquinones, cardiac glycosides, tannins, saponins and free reducing sugar while alkaloids are absent. The acetone extract of the plant.s leaves was subjected to extensive column and thin-layer chromatography on silica. This afforded a compound characterized as cupressuflavone, a biflavonoid. The structure was elucidated using spectroscopic techniques, - UV, IR, NMR (2-D) and MS
(Electrosspray Ionisation . ESI). Spectroscopic data obtained are consistent with literature values for cupressuflavone. Preparation of methylated and acetylated derivatives was carried out, for confirmation.
(Electrosspray Ionisation . ESI). Spectroscopic data obtained are consistent with literature values for cupressuflavone. Preparation of methylated and acetylated derivatives was carried out, for confirmation.
