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Effect of formulation variables on the hypoglycaemic activity of dried aqueous extract of Stachytarpheta angustifolia tablet formulations


A Isah
Y Ibrahim
E Abdulrahman
M Ibrahim
A Yaro

Abstract

Fingerprint was developed to study the effect of excipients on the hypoglycaemic activity of the tablets of aqueous extract of Stachytarpheta angustifolia (Mill) Vahl (Verbanaceae). The excipients studied were lactose, magnesium carbonate as diluents, maize starch, polyvinylpyrrolidone (PVP) and gelatin as binders. The biological method was used for the evaluation using a diabetogenic agent, alloxan. The results show that the method was effective in assessing the interactions where it was found that none of the added substances interfered with the hypoglycaemic activity of the aqueous extract of Stachytarpheta angustifolia (Verbanaceae).

Keywords: Fingerprint, Stachytarpheta angustifolia, Tablet excipients


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eISSN: 0189-8442