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Published:
Jan 27, 2005Keywords:
Pennisetum subangustum Haemostasis Platelet Bleeding
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Main Article Content
Platelet response to the ethanolic extract of Pennisetum subangustum in the albino Wistar rat
Abstract
Pennisetum subangustum, locally known as “fuur” in some populations in the Jos Plateau is used to stop bleeding in the event of an injury. The leaves of the plant were marshed and soxhlet extracted with ethanol for 72 hours. The extract of P. subangustum was then administered to albino Wistar rats. Platelet count, bleeding time and clotting time, were determined before and after the administration of the extract. Results show that the platelet count was reduced; bleeding time and clotting time prolonged. A precise mechanism of the haemostatic role of P. subangustum is yet to be established, and this is planned for in the next phase of the investigations. Any beneficial role ascribed to it for arresting bleeding is not supported by this study.
Key Words: Pennisetum subangustum; Haemostasis; Platelet; Bleeding.
Journal of Pharmacy and Bioresources Vol.1(1) 2004: 67-69
Key Words: Pennisetum subangustum; Haemostasis; Platelet; Bleeding.
Journal of Pharmacy and Bioresources Vol.1(1) 2004: 67-69
