Studies on wound healing properties of Crateva religiosa leaf extract

Abstract

Dried leaves of Crateva religiosa were extracted with methanol using a soxhlet extractor. The classes of phytocompounds present in the extract were determined and the LD₅₀  estimated in mice intraperitoneally. The extraction gave a yield of 14.6%. Alkaloids, carbohydrates, tannins, flavonoids, resins, proteins, oils, steroids and terpenoids were present. The extract had wound healing activity that was superior to that of penicillin. The faces of wound treated with the extract dried faster indicating that the extract had extrawound healing mechanism when compared to that of penicillin.

Keywords: Creteva religiosa, wound healing, phytochemisty, LD₅₀

Journal of Pharmaceutical and Allied Sciences, Vol. 7 No. 4 (2010)