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Effect Of 0.5%Glucose Intake On The Tear Production Of Normoglycemic Emmetropic Nigerians


CO Timothy

Abstract

Glocose the primary source of energy for body's cell metabolism is used up by the body via the activities of insulin that breaks down the glucose into glycogens which is stored up in cells. 0.5% glucose was administered to 50 normoglycemic subjects without fundal or vascular pathology of both sexes with a mean age of 22.27±2.70 years, to determine its effect on tear production. The induced effectswere checkedat 30mins interval till the values approximatedthe normal. The result showed aslight
decrease in tear production after 30mins (-1.74mmrepresenting 6.5%). Further decrease was noticed at 60mins -5.32mm(19.78%) andpeak decreasewas observedat 90mins (-7.66mmrepresenting28.48%. It slowly increased towards baseline at 120mins (-5.82mm representing 21.64%), and 150mins (-3.92mm, representing14.57%). This effect was significant (p>0.05) using Z-test statistical analysis. The reduction was observed to be more significant in females than in males probably due to hormonal differences. Exhaustive case history is advocated on patients who report for eye care immediately after feeding on heavy carbohydrate diet at least for the first 90mins as this may reduce tear production leading to apparent dryeyeinorder toguardagainstmisdiagnosis.

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eISSN: 0795-0039
print ISSN: 0795-0039