Haematological Parameters in Open Angle Glaucoma Patients

Abstract

There is potential for blood related factors to affect aqueous production or optic nerve functions. There have been relationships between inflammatory cell count and glaucoma. Eosinophils have inverse relationship with steroids which is used to induce ocular hypertension. Here we compare hematological parameters for a group of 68 chronic open-angle glaucoma (OAG) patients and a non-glaucomatous group of 71. In our hematological analysis we determined the concentration of the various white blood cells (WBC), and packed cell volume (PCV). In the blood cell analysis, we found a significantly lower eosinophil in the glaucoma group (2.54% to 4.03%). There were no significant differences for the PCV, (40.47% to 41.97%), white blood cell total/mm3 (5105.97 to 4802.98) Lymphocyte, (50% to 50.73%), Neutrophil, (44.8% to 42.5%), Monocyte, (1.76% to 1.97%), Basophil (0.35% to0.53%). Of the hematological characteristics considered, in the blood analysis we found only the eosinophil count to have a significant relationship to glaucoma.


Keywords: OAG, IOP, Eosinophils, Prostaglandin, Steroids.

Journal of Medicine and Biomedical Research Vol. 5 (1&2) 2007: pp. 35-40