Urethral stricture, changing patterns.

Abstract

In comparison with unaffected persons, individuals infected with HIV have undue predisposition to other infections including those of urinary tract. To assess this predilection to urinary tract infection (UTI) among this cohort, 158{59 (37%) males and 99 (63%) female} of them comprising mainly adolescents and young adults with confirmed HIV infection and attending Consultant Out patient Clinic of the University of Benin Teaching Hospital (UBTH) were evaluated for UTI through culture done on mid stream urine. The study carried out between September 2003 and May 2005 was prospective and cross sectional. Ten {(6.3%), one male and 9 females} patients had positive urine culture of uro-pathogenic organisms. Only 2 (20%) of these 10 patients had urinary symptoms of dysuria and loin pain. However fever was commoner among the patients with UTI as compared to those without it (54/148 or 36.5% vs 9/10 or 90.0%, χ2 =9.01, p<0.5). Urinary pathogens were Escherichia coli 5 (50%), Klebsiella species 3 (30%) and Staphylococcus aureus 1 (10%). In vitro sensitivity revealed that Escherichia coli and Klebsiella species were 100% sensitives to ofloxacin, 100% and 66.7% respectively to ciprofloxacin but completely resistant to cotrimoxazole, amoxicillin and clavulanic-acid potentiated amoxicillin. The adolescent/ young adult with HIV infection has enhanced risk of having UTI caused by similarly implicated organism in otherwise apparently health cohorts of comparable age bracket.


Keywords: Urinary Tract Infection, Adolescents, Human Immunodeficiency Virus

Journal of Medicine and Biomedical Research Vol. 5 (2) 2006: pp. 55-60