Diffuse neonatal hemangiomatosis, atrial setal defect and syringoma of the thigh: Case reoprt and literature review

Abstract

Vascular birthmarks are common in the neonatal period and may be either hemangiomas or vascular malformations. Hemangiomas are usually few benign, pediatric tumors of endothelial cell which may regress, however diffuse neonatal hemangiomatosis is a rarer syndrome characterized by hundreds of hemangiomas affecting the skin and visceral organs and  associated with poor prognosis. A male neonate is discussed who presented at birth with hundreds of cutaneous hemangiomas, arterio-venous mixed malformation and syringoma of the left thigh with an Atrial Septal Defect (ASD). Thrombocytopenia was absent. Skin lesions noted to be regressing daily but the tumor over the left thigh was static. Teratogencity was considered following ingestion of a supplement consumed throughout pregnancy. Psychosocial issues that need to be addressed remain bedrock in the management of these patients.

Keywords: Hemangiomatosis ,atrial septal defect,syringoma, ,thrombocytopenia, psychosocial