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Preparation, characterization and in vitro antimicrobial activity evaluation of thyme essential oil formulation to treat skin infections


N. Mebarki
M. Nabiev
H. Ziane
H. Chader
F. Fazouane

Abstract

The aim of the present study was to develop and evaluate a topical formulation containing Thymus fontanesii Boiss. & Reut essential oil that could serve as an antimicrobial agent for the treatment of various skin diseases caused by bacteria, yeast and dermatophytes. The selected formulation exhibited a significant antimicrobial activity against all tested strains, better consistency, good homogeneity, no skin irritation and good stability for six months at 25 ± 2°C. Our results demonstrate that the formulation could be used safely as topical preparation to treat skin diseases caused by the tested microorganisms into the future.


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print ISSN: 1112-9867