Copper-(s)-N-methylpyrrolidine-2-carboxylate catalyzed N-Arylation of N5h-1,2,5-thiadiazolidine 1,1-dioxides

Abstract

copper-catalyzed N-arylation of N⁵H-1,2,5-thiadiazolidine 1,1-dioxides derivatives (cyclic sulfamides) is  described. Reactions were carried out using Ullmann–Goldberg-type condensation with (S)-N-methyl- 2-carboxylate as the ligand, and N-arylated products were obtained with moderate to good yields. The  structures of the synthesized compounds were confirmed based on analytical and spectral data.

Keywords: Ullmann reaction; Goldberg reaction; N-arylation; 1, 2, 5-thiadiazolidine 1, 1-dioxides; aryl halide.