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Pterigium Excision With Application of Mitomycin-C In Enugu, Nigeria
Abstract
Aim: To evaluate the usefulness of mitomycin-C as it relates to modern techniques in the prevention and treatment of recurrent pterygium.
Patients and method: Patients with pterygium and recurrent pterygium were enrolled. Patients personal data including age, sex and surgical history were noted. The exclusion criteria applied were failure to comply with at least 6 months of follow-up, and patients whose primary surgeries were performed in centers not included in the study . Included also was a retrospective study of patients who had pterygium excisions with the same surgical technique but without application of any adjuvant.
Results: A total of 28 patients satisfied the inclusion criteria. Eighteen of them had surgery for the first time, 15 had re-surgery after initial excision with 5-fluorouracil. A total of 33 eyes were operated on as 5 of the patients had surgery in both eyes . The recurrence rate was 12.0%. For comparative analysis, 32 patients were studied retrospectively with recurrence noted in 20 (62.5%) of them.
Conclusion: The rate of recurrence in this study was found to be low with application of low dose mitomycin-C during bare sclera pterygium excision. Without any applications , recurrence rate was found to be as high as 62.5%. This procedure has been found to be simple, affordable and effective.
Key words: Recurrent pterygium, prevention, treatment, mitomycin-C.
[Jnl College Medicine Vol.7(1): 2002: 24-26]
Patients and method: Patients with pterygium and recurrent pterygium were enrolled. Patients personal data including age, sex and surgical history were noted. The exclusion criteria applied were failure to comply with at least 6 months of follow-up, and patients whose primary surgeries were performed in centers not included in the study . Included also was a retrospective study of patients who had pterygium excisions with the same surgical technique but without application of any adjuvant.
Results: A total of 28 patients satisfied the inclusion criteria. Eighteen of them had surgery for the first time, 15 had re-surgery after initial excision with 5-fluorouracil. A total of 33 eyes were operated on as 5 of the patients had surgery in both eyes . The recurrence rate was 12.0%. For comparative analysis, 32 patients were studied retrospectively with recurrence noted in 20 (62.5%) of them.
Conclusion: The rate of recurrence in this study was found to be low with application of low dose mitomycin-C during bare sclera pterygium excision. Without any applications , recurrence rate was found to be as high as 62.5%. This procedure has been found to be simple, affordable and effective.
Key words: Recurrent pterygium, prevention, treatment, mitomycin-C.
[Jnl College Medicine Vol.7(1): 2002: 24-26]
