Article Sidebar
Article Details
Issue
Section
Articles
JASEM has joined the Creative Commons Attribution License (CCAL). Therefore articles in JASEM are open access articles distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Main Article Content
Investigation Of Acute Toxicological Effects Of Diesels Fuel In Rats (Rattus rattus) Using Histopathological Methods
Abstract
Acute toxicological effects of diesel fuel in rats were investigated. The LD50 value was determined as 70.6gIkg using rats of 0.2kg body weight. Histopathological examination of rat tissues after exposure of rat groups to
0.9% saline (controlgroup), LD50 and LD100 of diesel fuel for 24 hour revealed black deposits and inplamination respectively in the pulmonary interstitium, and necrosis of the kidney and liver of rats administered with diesel fuel. From the international classification of the toxicity of chemicals based on their LD50 values, diesel fuel seemed to be relatively harmless, however, there is the need for caution in the use of the petroleum product as direct effect of it on tissues indicated toxicity
0.9% saline (controlgroup), LD50 and LD100 of diesel fuel for 24 hour revealed black deposits and inplamination respectively in the pulmonary interstitium, and necrosis of the kidney and liver of rats administered with diesel fuel. From the international classification of the toxicity of chemicals based on their LD50 values, diesel fuel seemed to be relatively harmless, however, there is the need for caution in the use of the petroleum product as direct effect of it on tissues indicated toxicity
