Synthesis and characterization of Cr (III)-ascorbic acid complex

Abstract

Ascorbic acid is a powerful antioxidant because of its ability to eliminate free radicals generated by the body. The ability of this compound to protect the body cells and its components from radicals has been proven. In this work, a complex of Cr (III) ascorbate was synthesized through the reaction of ascorbic acid and Chromium (III) chloride. The nature of the coordination between chromium ion and ascorbic acid was studied. The complex was characterized by UV-Visible, Infrared and ¹H NMR spectroscopy. The yield, melting point and solubility of the complex were determined. The solubility parameter suggested that the complex is mildly polar. Electronic spectrum of the complex showed ligand to metal charge transfer (LMCT) and d-d transition. FTIR spectrum of the complex showed a shift to lower frequency for C=O and OH functional groups. Spectroscopic characterization suggested the involvement of carbonyl and 2 hydroxyl group of ascorbic acid ligand in coordination with chromium (III) ion to form the complex. A tridentate geometry was proposed for the complex based on the spectroscopic studies. The Ascorbic acid behaved as a bidentate ligand towards Cr (III) ion. Finally, the ability of ascorbic acid to extract Cr (III) ions from environment or biological system is hereby assured.. The application of ascorbic acid in Cr chelation therapy is hereby recommended.