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Published:
Mar 31, 2020Keywords:
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Main Article Content
Phytochemical screening and study of in vitro antioxidant activities of the aqueous extract and the alcoholic (koutoukou extract) of Garcinia kola seeds (Guttiferea) collected in Abidjan (Ivory Coast).
Abstract
Objectives: Garcinia kola (Guttiferea) is a plant commonly found in West and Central Africa. Many biological activities such as anti-inflammatory, antimicrobial, antiviral and antioxidant are conferred because of its chemical composition. This work aimed to perform the triphytochemistry of two (2) extracts i.e. the aqueous extract and koutoukou (alcoholic extract) of G. kola seed, and to evaluate their antioxidant activities.
Methodology and results: The triphytochemical screening of the aqueous extract and the koutoukou extract were carried out. The DDPH radical scavenging test and the determination of the ferric ion reducer (FRAP) provided evidence of antioxidant activity. The average alcoholic degree of koutoukou samples varied between 42.33 ° ± 4.04 and 62 ° ± 3.00. Phytochemical screening revealed the presence of flavonoids, saponosides, polyphenols, polyterpenes, sterols, Catechin tannins and the absence of Gallic tannins, quinone substances and alkaloids in both extracts (aqueous extract and koutoukou extract). The profile of the antioxidant activity of the study, using the DDPH radical trapping test and the FRAP method, respectively revealed that Ci 50 (65.86 ± 1.17 μg /mL) and the reducing power of the Ferric ion (125. 4 ± 4. 91 mg / mL) of koutoukou extract from G. kola seeds is statistically significant.
Conclusion and applications of the results: Catechin tannins, saponosides, sterols, polyterpenes, flavonoids and polyphenols were found in the aqueous extract and koutoukou extract of Garcinia kola seeds. Thus, the antioxidant activity of the koutoukou extract of G. kola seeds was greater than that of the aqueous extract. The koutoukou extract of seeds of G. kola, still keeps the biological properties conferred on G. kola. The doses and mechanism of action of this cocktail deserve to be highlighted in order to propose it as an Improved Traditional Medicine (MTA). However, this cocktail can be used and recommended to combat oxidative stress and its consequences for good health.
