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Published:
Aug 29, 2018DOI:
10.4314/jab.v122i1.8Keywords:
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Main Article Content
Évaluation de l’activité antibactérienne des extraits de feuilles de Solanum torvum Swartz (Solanaceae) sur la croissance in vitro de 3 souches d’entérobactéries
Abstract
Objectif: Établir des bases scientifiques de l’action antibactérienne de Solanum torvum Swartz (Solanaceae), une plante médicinale utilisée en médecine traditionnelle contre les infections bactériennes.
Méthodologie et Résultats: Les extraits issus de cette plante ont été testés sur la croissance in vitro des souches de E. coli, de K. pneumoniae et de Salmonella sp en milieu liquide et solide de Mueller-Hinton. Les résultats ont révélé que ces extraits ont une activité antibactérienne dose-dépendante sur ces souches bactériennes utilisées. Cependant, l’extrait acétonique 100% a un meilleur potentiel antibactérien sur la souche de E. coli (CMI = 6,25 mg/mL et CMB = 1,563 mg/mL) que sur c el l e d e Salmonella sp (CMI = 3,125 mg/mL et CMB = 6,25 mg/mL) et de K. pneumoniae (CMI = 6,25 mg/mL et CMB = 12,5 mg/mL).
Conclusion et application des résultats: Cet extrait peut être utilisé pour la mise au point de phytomédicaments contre les gastroentérites à E. coli et à Salmonella sp.
Mots clés: Antibactérienne, extraits, Solanum torvum, in vitro, gastroentérites
English Abstract
Objective: Establish scientific bases of the antibacterial action of Solanum torvum Swartz (Solanaceae), a medicinal plant used in traditional medicine against the bacterial infections.
Methodology and Results: The extracts resulting from this plant were tested on in vitro growth of the stocks of E. coli, K. pneumoniae and Salmonella sp in Mueller-Hinton broth and Mueller-Hinton naehrboden agar. The results have revealed that these extracts have dose-dependent action against bacteria targeted. However, the 100% acetonic extract has a better antibacterial potential on the stock of E. coli (MIC = 6.25 mg/mL and MBC = 1.563 mg/mL) than on Salmonella sp (MIC = 3.125 mg/mL and MBC = 6.25 mg/mL) and of K. pneumoniae (MIC = 6.25 mg/mL and MBC = 12.5 mg/mL).
Conclusion and application of the results: This extract can be used to formulate a drug against the gastroenteritis with E. coli and Salmonella sp.
Keywords: Antibacterial, extracts, Solanum torvum, in vitro, gastroenteritis
