Sélection de quelques plantes médicinales du Zerhoun (Maroc centrale) pour l’activité antibactérienne contre Pseudomonas aeruginosa

Abstract

Objective: To evaluate the in vitro antibacterial activities of two extracts (Aqueous extract and ethanolic extract) from the leaves of fourteen medicinal plants found in Zerhoun (central Morocco) on the growth of six strains of Pseudomonas aeruginosa.
Methodology and Results: The method of diffusion in solid and macromethod of dilution in liquid medium from active extract were used for antibacterial testing. The results showed that aqueous extracts were more active than the ethanol extracts. The plant extracts were more active against pigmented strains (pyocyanin) than against non-pigmented strains. Eight plants showed antibacterial activity against one or more bacterial strains. The aqueous extract of Eucalyptus gomphocephala presented the highest anti Pseudomonas aeruginosa activity against all strains tested with zones of inhibition between 16 and 18.5 mm, having an MIC value (6.25-12. 5mg/ml) and MBC (6.25-25mg/ml).
Conclusion and Application: According to this study results, water was the best solvent in the concentration of the active ingredients of the plants. In addition, the antibacterial activities of the extracts from the leaves of eucalyptus in this study could justify the therapeutic use of this plant in traditional medicine in the treatment of many bacterial infections.

Keywords: antibacterial activity; aqueous extracts; ethanol extracts; Pseudomonas aeruginosa; eucalyptus gomphocephala.