Aerobic bacteriological profile and antibiotic resistance of surgical site infections in surgery ward of Teritiary care hospital Mahaboobnagar

Abstract

Background: Surgical Site Infections (SSI) constitutes a major fraction of nosocomial infections and occurs in superficial incisional, and organ/ space locations. In developing countries, surgical site infections (SSIs) are imposing a heavy and potentially preventable burden on both patients and healthcare providers.
Objectives: The aim of this Study was to isolate and identify organisms from SSI and to study their antibiotic resistance pattern.
Methods: This prospective study was conducted in Microbiology department associated with tertiary care hospital S.V.S Medical College and Hospital over a period of 24 months (from November 2010 to December 2012) were included. Isolates were identified according to the standard protocols and antibiotic sensitivity was done by Kirby Bauer disc diffusion technique.
Results: Out of 752 samples 150 samples were culture positive. In that Staphylococcus aureus (49.33%) is most common followed by CONS (14%), Pseudomonas sps (9.33%), Acinetobacter (5.33%), Citrobacter and Klebsiella sps (4.66%), E.coli and Proteus sps (4%). Enterococci sps (2.66%) and Streptococci sps (2%). Staphylococcus aureus showing nearly 56.75% resistance to Cefoxitin. Majority of Gram negative organisms are resistant to third generation cephalosporins like Ceftazidime, Cefotaxime (51%) and are uniformly sensitive to Imipenem and Tigecycline (100%).
Conclusions: Emerging antibiotic resistance in the clinical isolates of Surgical Site Infections is a serious issue which has to be dealt with appropriate antimicrobial therapy and proper management.