The effects of crude extracts of Pterocarpus soyauxii on the hematology of albino wistar rats

Abstract

The effects of crude extract of Pterocarpus soyauxii leaves on the red blood cell (RBC), white blood cell (WBC), parked cell volume (PCV) and hemoglobin concentration (HBC) were studied in 30 albino rats of both sexes weighing between 150 and 200 g. The rats were divided into 3 groups of 10 rats each. Group I served as the control, while the other two served as the experimental groups that received 0.5 and 1.0 ml of the crude extract of Pterocarpus soyauxii leaves. The extract at the dose of 0.5 ml significantly increased RBC, HBC and PCV, while 1.0 ml slightly decreased almost all the parameters measured. In conclusion, the effect of Pterocarpus soyauxii on blood parameters is dose dependent. At lower dosage, it increases the hematological parameters and could therefore be beneficial in the treatment of anemic conditions at this level, but has opposite effect at higher dosage.

Keywords: Pterocarpus soyauxii, hematological parameters, albino wistar rats, anemia

International Journal of Natural and Applied Sciences, 5(4): 361-364, 2009