Effects of Relaxation Times from the Bloch Equations on Age Related Changes in White and Grey Matter

Abstract

This research work presented the analytical method of using T1 and T2 relaxation rates of white matter and grey matter to distinguish the passage of time on human organs. A time-dependent model equation evolved from the Bloch Nuclear Magnetic Resonance equation was solved under the influence of the radio frequency magnetic field [rfB1(x, t) ̸= 0] and in the absence of radio frequency magnetic field [rfB1(x, t) = 0]. The general solution was considered in three cases. Analysis of the solutions obtained revealed that the rate of decrease of the white matter was faster than that of the grey matter. Between 100 and 400 seconds the difference is more noticeable.