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Effects of Gymnema lactiferum leaf on serum glucose and cholesterol levels of streptozotocin induced diabetic rats
Abstract
Gymnema lactiferum var. lactiferum is distributed in Assam, Malay Peninsula, Malaysia and Sri Lanka. The leave of this plant is popular as a treatment for diabetes. However, scientific data is not available on this. The present study was designed to determine the effects of G. lactiferum leaf on glycaemic and lipidemic status in type 2 diabetic rats. Fasting blood sugar (FBS) levels of the diabetic rats reduced significantly (p=0.001) after 28 days of the treatment. A significant decline (p=0.015) was also seen in the serum total cholesterol levels. Results indicate that G. lactiferum leaf powder possesses hypoglycaemic and hypocholesterolaemic effects on type 2 diabetic rats and therefore it is postulated that it would make a good functional food for type 2 diabetic subjects.
Keywords: Gymnema lactiferum var. lactiferum, Type 2 diabetic rats, hypoglycaemic, hypocholesterolaemic
