Article Sidebar
Article Details
Submission of a paper for publication implies the transfer of the copyright from the author(s) to the publisher upon acceptance. International Formulae Group is therefore the copyright holder after publication of an article in International Journal of Biological and Chemical Sciences, and published articles should not be used for commercial purpose without the written consent of the Editor-in-Chief. They are licensed under a Creative Commons Attribution-Non Commercial-Share Alike 4.0 International License.
Main Article Content
Isolation and antibacterial activity of triterpenes from Euphorbia kamerunica Pax
Abstract
Two known compounds, friedelin and epifriedelinol were isolated from Euphorbia kamerunica Pax. The compound’s structures were established on the basis of spectral analysis. The antibacterial activities of these compounds and the ethyl acetate extract were established on Pseudomonas aeruginosa, Salmonella typhii and Staphylococcus aureus. The extract displayed higher inhibition activities on the bacteria than the isolated compounds. The zones of inhibition of the extracts were between 9.0 and 30.5 mm, with the highest extract activity on Staphylococcus aureus. The minimum inhibition concentration (MIC) values of the isolated triterpenes were between 7.5 - 10 μg/ml.
© 2010 International Formulae Group. All rights reserved
Keywords: Euphorbia kamerunica, friedelin, epifriedelinol, antibacterial activity, MIC.
