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Incidence of adenovirus detected by immunoenzymatic assay from children hospitalized with acute gastroenteritis in Douala, Cameroon
Abstract
Adenovirus is recognized as the most common cause of severe gastroenteritis in children less than 5 years of age. Due to the lack of recent reports about the surveillance of enteric adenovirus (EAd) infection in Cameroon, in this study we assessed the prevalence rate of HAV infection on 65 stool samples belonging to 65 paediatric patients hospitalized with acute gastroenteritis in the period October 2005-December 2005. The faecal samples were submitted to virological investigations by enzyme-linked immunosorbent assay (ELISA).
Single adenovirus infections were detected in 43.1% (28/65 cases). According to age distribution, 44.7% (17/38 cases) of adenovirus infected children was one month to 5 years, 30.8% (4/13 cases) was in the 6-10 year old age and 50.0% (7/14 cases) was in the 11-15 year age group. The epidemiological aspects of adenovirus infection, will contribute to assess the magnitude of the problem of adenovirus in different settings and to devise strategies for intervention.
Keywords: Epidemiology, enteric adenovirus, acute gastroenteritis, hospitalized children
International Journal of Biological and Chemical Sciences Vol. 2 (2) 2008: pp. 220-223