Article Sidebar
Published:
Jan 13, 2025Keywords:
Article Details
Submission of a paper for publication implies the transfer of the copyright from the author(s) to the publisher upon acceptance. International Formulae Group is therefore the copyright holder after publication of an article in International Journal of Biological and Chemical Sciences, and published articles should not be used for commercial purpose without the written consent of the Editor-in-Chief. They are licensed under a Creative Commons Attribution-Non Commercial-Share Alike 4.0 International License.
Main Article Content
Evaluation of the antioxidant properties of the hydromethanolic extract and Triterpenes isolated from the roots of Hallea ledermannii
Abstract
Hallea ledermannii belongs to the Rubiaceae family. It is traditionally used to managed pathologies such as dysentery, fever, malaria, gonorrhea and other diseases. The present study aimed to report chemical composition and antioxidant properties of Hallea ledermannii root bark extracts. Antioxidant activity of the hydromethanolic extract was evaluated by the DPPH and ABTS methods. Phytochemical screening showed tannins, polyphenols, flavonoids, saponosides, leuco-anthocyanins, reducing compounds, polyterpenes and sterols. The total concentrations of polyphenols, flavonoids, tannins and anthocyanins contained in the extract were respectively estimated at 385.62 mg Eq acG/g, 287.715 mg Eq Q/g, 145.54 mg Eq acT/g and 0.42 mg Eq Cyanide glucoside/100g. Six known compounds: ursolic acid (1), uncaric acid (2), quinovic acid (3), 3-oxoquinovic acid (4), quinovic acid 3-O-β-D-glucopyranoside (5), quinovic acid-3-O-β-D-quinovopyranoside (6) were isolated from Hallea ledermannii roots extracts. The inhibition percentages of Trolox at a concentration of 10 mg/ml are 96.20% and 99.76% for DPPH and ABTS respectively.
