Assessment of the immuno-nutritional status of malnoutrished people living with HIV at ‘‘Notre Dame des Apôtres’’ hospital in Sarh/Chad

Abstract

Human immunodeficiency virus (HIV) infection leads to immune deficiency, reduced nutrient absorption, and malnutrition. Malnutrition  also affects the immune system and contributes to the progression of HIV. The objective of the present study was to evaluate the  immuno-nutritional state of malnourished people living with HIV/AIDS followed at the Notre Dame des Apôtres Hospital in Sarh/Chad.  For this we performed the assay of biochemical parameters including total proteins, transaminases (ALT, AST), alkaline phosphatase and  immunoglobulin E (IgE) was done 36 malnourished subjects living with HIV/AIDS aged at least 18 years at the People Living with HIV  (PLHIV) service were identified during this study. The sample population was dominated by the female sex with 75% of cases, i.e. a sex  ratio of 0.33. The most represented age group was 18 to 40 years old with 47.22%. The results obtained showed that 52.94% of the  samples had a level below the standard in total proteins, 100% of the samples analyzed showed a level extremely higher than the  standard in ASAT, ALT and alkaline phosphatase and 60% of individuals presented a higher level of IgE. From these results it could be  concluded that malnutrition and HIV lead to an immuno-nutritional deficit giving way to other opportunistic infections.