Ethnobotanical study and antioxidant activity of anti-hepatitis plants extracts of the COMOE province, Burkina Faso

Abstract

Acute hepatitis B and its complications cause 800000 and 3300 deaths each year respectively in the world and in Burkina Faso. In Burkina Faso, the majority of the population uses medicinal plants to treat hepatitis. The present study consisted to identify the medicinal plants used to treat hepatitis in COMOE province of Burkina Faso. Extracts from the most cited species were screened for their antioxidant capacity (using ABTS and FRAP methods) and their content in phenolics. Thirty-two anti-hepatitis species belonging to 29 genera and 20 families were recorded in the COMOE province. Extracts from Diospyros mespiliformis and Terminalia macroptera showed the best antioxidant activities (1.17 ± 0.00 mM TEAC/g and 70.77 ± 0.4 μM ET/g ; 1.09 ± 0.03 mM TEAC/g and 81.17 ± 0.5 μM TE/g extract, respectively).The same extracts exhibited the highest total phenolic contents. Low correlation has been obtained between total phenolic contents and antioxidant capacity (TEAC) of the extracts. This finding suggests that non-phenolic antioxidant compounds would be involved in the bioactivity of these species. This study constitutes a contribution in the safeguarding of traditional hepatoprotective medicinal knowledge of COMOE province of Burkina Faso.

Keywords: Anti-hepatitis plants, antioxidant activity, COMOE province, Burkina Faso.