Review Of Lymphoma Classification

Abstract

Lymphomas are malignant neoplasms characterized by the proliferation of cells native to the lympoid tissue i.e lymphocytes, histiocytes and their precursors and derivatives. These heterogenous neoplasms are of the monoclonal origin. Lymphoma have been broadly classified into two main categories; Hodkin disease (HD) and non- Hodgkin lymphoma (NHL). Where as HD has had a fairly stable classification scheme over the years since Rye classification into being, NHL has had the most unstable classification schemes. First to come into being were Gall and Mallory, Rappaport and Doffman classifications. Others that followed later were Benneth, farrer- Brown Henry, Lukes – Collins and Kiel classifications which were later harmonized by a working formulation for clinical usage. The last to come into being was the REAL classification which has been modified and adopted by the W.H.O. The working forrmulation for clinical usage is still the most workable classification for our own environment.

Keywords: Historical review; Lymphoma Classification

Highland Medical Research Journal Vol. 4 (2) 2006 pp. 1-8