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Liver function profile and benzom
Abstract
Objective: To determine the outcome of hippuric acid test on both subjects and control used in order to evaluate the conjugating capacity of the liver in the two groups.
Materials and Methods: 34 patients with idiopathic hypertension and 18 normal subjected use as the control were subjected to different laboratory investigation of liver functions following an informal consent. The hippuric acid test was conducted in all of them to evaluate the conjugating capacity of the liver.
Results: A marked derangement of hippuric acid test was seen in patients with idiopathic hypertension when compared with normal subjects used as control.
Conclusion: The result of this preliminary investigations is no conclusive evidence that this defect bears any direct relationship to the hypertension seen in this group, they must however be considered significant. It is suggested that the disturbance of this mechanism which inevitablt would interfere with elimination of certain hypertension inducing hormones and their breakdown products may at least be partially contributory to the elevated blood pressure seen in this group.
Keywords: primary hypertension, hippuric acid conjugation test, Nigerians Highland Medical Research Journal Vol. 3(2) 2005: 38-44
Materials and Methods: 34 patients with idiopathic hypertension and 18 normal subjected use as the control were subjected to different laboratory investigation of liver functions following an informal consent. The hippuric acid test was conducted in all of them to evaluate the conjugating capacity of the liver.
Results: A marked derangement of hippuric acid test was seen in patients with idiopathic hypertension when compared with normal subjects used as control.
Conclusion: The result of this preliminary investigations is no conclusive evidence that this defect bears any direct relationship to the hypertension seen in this group, they must however be considered significant. It is suggested that the disturbance of this mechanism which inevitablt would interfere with elimination of certain hypertension inducing hormones and their breakdown products may at least be partially contributory to the elevated blood pressure seen in this group.
Keywords: primary hypertension, hippuric acid conjugation test, Nigerians Highland Medical Research Journal Vol. 3(2) 2005: 38-44
