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Haemolytic Uraemic Syndrome In Nigerian Infants
Abstract
Diarrhoea is one of the major causes of hospitalization, morbidity and mortality in children. Haemolytic uraemic syndrome (HUS) may occur as one of the complications associated with diarrhoea in acute gastroenteritis.
Objectives: The objective of this study is to present laboratory evidence of HUS in hospitalized infants with acute gastroenteritis.
Method: Blood urea, electrolytes, creatinine, full blood count and platelets were investigated using standard techniques in children who presented with acute diarrhoea. Those with transient impairment of renal functions were excluded.
Results: The Results indicate that 29 out of 181 (16%) had elevated levels of potassium, urea, creatinine, total white blood cell count, neutrophil, while there was diminished levels of bicarbonate, packed cell volume, haemoglobin and platelet count. Statistically significant difference was observed in all values (p<0.001) when compared with those infants without laboratory evidence of HUS who had acute diarrhoea.
Conclusion: It is concluded that HUS is a common complication in infantile diarrhoea and physicians should therefore be on alert, good sanitary condition and exclusive breast feeding may reduce the incidence of HUS in infants.
Highland Medical Research Journal Vol. 3 (1) 2005: 7-10
Objectives: The objective of this study is to present laboratory evidence of HUS in hospitalized infants with acute gastroenteritis.
Method: Blood urea, electrolytes, creatinine, full blood count and platelets were investigated using standard techniques in children who presented with acute diarrhoea. Those with transient impairment of renal functions were excluded.
Results: The Results indicate that 29 out of 181 (16%) had elevated levels of potassium, urea, creatinine, total white blood cell count, neutrophil, while there was diminished levels of bicarbonate, packed cell volume, haemoglobin and platelet count. Statistically significant difference was observed in all values (p<0.001) when compared with those infants without laboratory evidence of HUS who had acute diarrhoea.
Conclusion: It is concluded that HUS is a common complication in infantile diarrhoea and physicians should therefore be on alert, good sanitary condition and exclusive breast feeding may reduce the incidence of HUS in infants.
Highland Medical Research Journal Vol. 3 (1) 2005: 7-10
