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Establishment Of A Local Biochemical Reference Range: Jos University Teaching Hospital Experience
Abstract
Objective: The objective is to establish a local biochemical reference range for neonates in Jos environment.
Materials and Methods: Three hundred and fifty normal full term babies were studied at birth for the purpose of establishing reference values for calcium, inorganic phosphate, Alkaline phosphatase, total protein and Albumin. The babies were selected from major delivery centers in Jos and the collection span fro fifteen months. Exclusion criteria for the selection includes apgar score of less than 6/10, birth weight of less than 2.6kg and obvious signs of distress at birth..
Result: The results of the analysis of the cord blood samples were as follows:- Calcium (mean = 2.4mmol/L and range 2.0 = 2.8 mmol/L) iorganic phosphate, (mean 1.6 mmol/L and range 1.1 = 2.1 mmol/L) Alkaline phosphates (mean 52 IU/L and range 30 = 74 IU/L) total protein (mean 67 g/L and range 59 – 76 g/L) albumin (mean 33 g/L and range 28 – 38 g/L).
Conclusion: There has been no previous studies on these variables in our environment, hence these figures can be taken as the local biochemical reference range of this age group.
This is to enable us interpret our laboratory data more meaningfully. This is vital for us to be able to manage effectively the metabolic disorders involving these variables in neonatal period in our environment. .
Key words: Reference value, neonate, environment.
Highland Medical Research Journal Vol.1(1) 2002: 17-20
Materials and Methods: Three hundred and fifty normal full term babies were studied at birth for the purpose of establishing reference values for calcium, inorganic phosphate, Alkaline phosphatase, total protein and Albumin. The babies were selected from major delivery centers in Jos and the collection span fro fifteen months. Exclusion criteria for the selection includes apgar score of less than 6/10, birth weight of less than 2.6kg and obvious signs of distress at birth..
Result: The results of the analysis of the cord blood samples were as follows:- Calcium (mean = 2.4mmol/L and range 2.0 = 2.8 mmol/L) iorganic phosphate, (mean 1.6 mmol/L and range 1.1 = 2.1 mmol/L) Alkaline phosphates (mean 52 IU/L and range 30 = 74 IU/L) total protein (mean 67 g/L and range 59 – 76 g/L) albumin (mean 33 g/L and range 28 – 38 g/L).
Conclusion: There has been no previous studies on these variables in our environment, hence these figures can be taken as the local biochemical reference range of this age group.
This is to enable us interpret our laboratory data more meaningfully. This is vital for us to be able to manage effectively the metabolic disorders involving these variables in neonatal period in our environment. .
Key words: Reference value, neonate, environment.
Highland Medical Research Journal Vol.1(1) 2002: 17-20
