Resistance pattern of Staphylococcus aureus isolated from surfaces at the State specialist Hospital, Osogbo, Osun State, Nigeria

Abstract

Background: Staphylococcus aureus is one of the most highly resistant bacterial pathogens that have been increasingly reported around the world. This study focused on the isolation and antibiotic sensitivity patterns of Staphylococcus aureus isolated from Osun State Specialist hospital, Asubiaro environment, Osogbo, Osun state.

Methods: A total of 36 swab samples were collected from different spots within the units/wards of the hospital and susceptibility test was carried out on identified S.aureus using disc diffusion method. The susceptibility results were interpreted using CLSI, 2011 criteria.

Results: Out of a total of 269 S.aureus isolates, 47 isolates demonstrated hemolysis. 32(68.08%) strains out of 47 hemolytic isolates demonstrated beta-hemolysis while 15(31.91%) strains demonstrated alpha-hemolysis. The percentage distribution of antibiotics susceptibility test showed that the hemolytic strains were mostly resistant to Ampicillin (100.00%), Tetracycline (78.12%), Chloramphenicol (56.25%), Ciprofloxacin (34.38%) and the least was Gentamicin (15.62%).

Conclusion: There is the need for consistent on-going antimicrobial surveillance for important and commonly isolated clinically significant pathogens of Staphylococcal species to form the basis for developing and implementing measures that can reduce the burden of antimicrobial resistance and prevent a possible impending public health problem. The study therefore evaluated the incidence of hemolytic strain and antibiotic sensitivity pattern of Staphylococcus aureus isolated from the hospital environment.

Keywords: Staphylococcus aureus, Antibiotics, Hospitals