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Published:
Sep 18, 2014DOI:
10.4314/gmj.v48i3.3Keywords:
Article Details
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Main Article Content
Therapeutic effect of continuous exercise training program on serum creatinine concentration in men with hypertension: A randomized controlled trial
Abstract
Background: Creatinine (Cr) has been implicated as an independent predictor of hypertension and exercise has been reported as adjunct therapy for hypertension. The purpose of the present study was to investigate the effect of continuous training programme on blood pressure
and serum creatinine concentration in black African subjects with hypertension.
Methods: Three hundred and fifty seven male patients with mild to moderate (systolic blood pressure [SBP] between 140-180 & diastolic blood pressure [DBP] between 90-109 mmHg) essential hypertension were age matched and randomly grouped into continuous & control groups. The continuous group involved in an 8 weeks continuous training (60-79% HR reserve) of between 45minutes to 60 minutes, 3 times per week, while the control group remain sedentary. SBP, DBP, VO2max, serum Cr, body mass index (BMI), waist hip ratio (WHR) and percent (%) body fat. Analysis of
covariance (ANCOVA) and Pearson correlation tests were used in data analysis.
Results: Findings of the study revealed significant decreased effects of continuous training programme on SBP, DBP, Cr, BMI, WHR, % body fat and significant increase in VO2max at p< 0.05. Serum Cr is significantly
and negatively correlated with SBP (-.335), DBP (.194), BMI (.268), WHR (-.258) and % body fat (-.190) at p<0.05.
Conclusion: The present study demonstrated a rationale bases for the adjunct therapeutic role of moderate intensity continuous exercise training as a multitherapy in the down regulation of blood pressure, serum Cr, body size and body fat in hypertension.
Key words: Hypertension; Blood pressure; Creatinine; body size; body fat; Africa.
