An evaluation of the efficacy of indocid (Indometacin) for the control of some laboratory and wild rodents

Abstract

Rodentsare well-known pests of stored and cultivated agricultural products. Their control is of great concern to human societies worldwide. Different rodenticides exist but most of these pose varying degrees of risk to the  general public. The study aims to establish the efficacy of a human anti-inflammatory drug, Indocid, as a potential rodenticide, using the widely-used Baraki as a reference rodenticide. Doses of indocid found to be lethal to laboratory rats (Rattus rattus) were lower than that of Baraki and, for a given concentration of active ingredients, death occurred relatively faster in indocidadministered than baraki-administered rats. Indocid further proved lethal to five species of wild rodents. There is the need for further work on recommended lethal doses required for the control of the various wild rodent
species.