The effect of Treculia africana African breadfruit on serum electrolyte enzyme and some haematological parameter in rat: a sub-chronic study

Abstract

A sub-chronic effect of diet of Treculia africana (Bread fruit BF) on serum electrolyte, enzyme and some haematological parameters in rats was studied. The test-diets were administered for 21 days after which, serum electrolyte enzyme and heamatological parameters were assayed. The control group were similarly treated but given normal diet The result showed that serum sodium (Na+) of rats given bread fruit diet of 10% and 20% respectively were significantly (P<0.001) and P<0.05) lower, but significantly (P<0.00) higher for those given BF of 100% when compared with control. The potassium and chloride ion levels in test and control groups were not significantly different. Calcium ion levels in the animals 10% and 20% respectively were not significantly different but the Ca2+ levels in those given BF 100% was significantly (P<0.01) lower compared with control. The bicarbonate ion levels were significantly (P<0.01) higher in test than control. Serum levels of ALT and ALP were significantly (P<0.001) higher in test than the control. The AST levels in animals given 10% and 20% BF were not significantly different but those given BF 100% was significantly (P<0.001) higher compared with control. The breadfruit diet when consumed without enriching food supplement decreased RBC, HB, PCV, MCHC indicating microcytic hypo-chronic anaemia and possible hepato cellular damage as shown in increase liver enzymes.

KEY WORD: Bread Fruit, enzyme, blood parameter and rats.