Ficus exasperata: effects on diabetes mellitus in an experimental rat model

Abstract

Effect of Ficus exasperata (Vahl) leaf on hyperlipidaemia, hypercholesterolaemia and hyperketonaemia associated with alloxan-induced diabetes mellitus were studied. One week oral administration of an aqueous extract of the leaf to alloxan-induced diabetic rats decreased plasma total triacylglycerol levels. Similarly, cholesterol and b-hydroxybutyrate concentrations were significantly (p<0.05) reduced. Results indicate that F. exasperata leaf possesses effective lipid lowering properties in diabetic rats.


Key words: Ficus exasperata, alloxan-induced diabetes mellitus, triacylglycerol, cholesterol, b-hydroxybutyrate.


(Global Journal of Pure and Applied Sciences: 2003 9(4): 529-532)