Testicular And Renal Toxicity In Rats Administered Extracts Of Heinsia Crinita Leaves

Abstract

Crude aqueous extracts of the black variety of Heinsia crinita leaves, a vegetable commonly consumed in southern Nigeria, were orally administered to albino rats of Wistar strain for seven days.
Organopathology of test animals showed no histological changes in liver, heart and brain tissues, compared with control. However, kidneys and testes of test animals showed significant changes in cytological ultra-structure. The paper discusses the possibility of renotoxicity as well as reproductive toxicity to males of human consumers, by extrapolation.


(Global Journal of Pure and Applied Sciences: 2002 8(2): 253-258)