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Toxicological effects of garlic (Allium sativum) on some haematological and biochemical parameters in rat


E. S. Bartimaeus
R. E Agbor

Abstract

The toxicological effect of garlic (Allium sativum) on some haematological and biochemical parameters in albino rats was studied. High doses of garlic infusion were found to cause a significant decrease (p<0.05) in the concentration of haemoglobin, packed cell volume, lymphocyte count, aspartate aminotransferase and alanine aminotransferase. The total white blood cell count and differential leucocyte counts (especially neutrophils and eosinophils) showed a significant increase (p< 0.05) consistent with high doses of garlic infusion. Red cell morphology was also appreciably affected.



Keywords:Haemoglobin (Hb), packed cell volume (PCV), lymphocyte, aspartate aminotransferase (AST) and alanine aminotransferase (ALT).

[Global Jnl Environ Sci Vol.2(1) 2003: 11-16]

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eISSN: 1596-6194