Toxicological effects of garlic (Allium sativum) on some haematological and biochemical parameters in rat

Abstract

The toxicological effect of garlic (Allium sativum) on some haematological and biochemical parameters in albino rats was studied. High doses of garlic infusion were found to cause a significant decrease (p<0.05) in the concentration of haemoglobin, packed cell volume, lymphocyte count, aspartate aminotransferase and alanine aminotransferase. The total white blood cell count and differential leucocyte counts (especially neutrophils and eosinophils) showed a significant increase (p< 0.05) consistent with high doses of garlic infusion. Red cell morphology was also appreciably affected.



Keywords:Haemoglobin (Hb), packed cell volume (PCV), lymphocyte, aspartate aminotransferase (AST) and alanine aminotransferase (ALT).

[Global Jnl Environ Sci Vol.2(1) 2003: 11-16]