Evaluation of antipyretic potential of Eclipta prostrate Linn. leaf extract in rats

Abstract

The methanol extract of leaves of Eclipta prostrate was tested for its antipyretic effects on rats. The extract (200 and 300 mg/kg, po) showed significant reduction of yeast-induced pyrexia in rats with respect to the control group. The antipyretic activity of the extract was comparable to that of the standard prototype, paracetamol.

Keywords: antipyretic, yeast-induced pyrexia, Eclipta prostrata, leaves, methanol extract

Ethiopian Pharmaceutical Journal Vol. 24, 2006: 71-73