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Jun 26, 2023Keywords:
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Main Article Content
Prevalence and drug susceptibility pattern of urinary tract infections among war disabled patients of Denden Hospital, Asmara, Eritrea
Abstract
Background: Urinary Tract Infections (UTIs) are the most common bacterial infections. The objective of the study was to assess UTI prevalence, common bacterial pathogens responsible for UTI, and the drug susceptibility pattern of bacteria towards commonly used drugs for UTI treatment among war- disabled patients admitted to Denden Military Hospital, Asmara, Eritrea.
Methods: A prospective cross-sectional study was conducted among 236 war veterans who were disabled during the war and took treatment at Denden Military Hospital.Midstream urine samples were collected in culture bottles. All collected urine samples were then cultured on different bacteria culture media. Biochemical tests were performed on posi-tive urine cultures based on significant bacteriuria as per the Kass count (>105 organisms/mL). Antimicrobial susceptibility tests were performed to analyze the resistance/ susceptibility pattern. Statistical Package for Social Services, version 20.1 was used for data entry and analysis.
Results: The overall prevalence of UTI was 81.7% (193/236). The common isolates were Escherichia coli (E.coli) 73(36.8%) followed by Staphylococcus aureus (S. aureus)38(19.1%). Usage of catheters with culture positivity was 22 (95.6%), 58 (95%), and 38(90.4%) for suprapubic, Condom, and Urethral Catheters, respectively. The antibiogram showed 62(84.9%) isolates of E.coli were resistant to Nitrofurantoin, while Staphylococcus aureus was found resistant to Tetracycline 25 (65.7%).
Conclusion: The results showed that most of the disabled patients included in the study were infected with UTI, and the most common pathogen isolated was E. coli followed by S. aureus. Based on the antimicrobial susceptibility test, the drug of choice for Gram- negative bacteria can be Amikacin, Gentamycin, and Cefalexin. While for Gram-positive bacteria it can be Ampicillin.
