Association between COVID-19 Diagnosis and In-Hospital Mortality of Hospitalized patients with ST-Segment ElevationMyocardial Infarction

Abstract

Introduction: The 2019 coronavirus disease pandemic (Covid-19) is the worst global health crisis right now. The clinical course of  covid-19 is often accompanied by hypercoagulation state, which means that COVID-19 patients could develop a number of cardiac  conditions, such as myocarditis, stress-induced cardiomyopathy, etc. The possibility of morbidity as well as mortality is increased among  individuals with COVID-19 who have ST-elevation myocardial infarction (STEMI) in comparison with patients without the virus who are the same gender and age.

Subjects and methods: We collected data from records in the form of personal history, comorbidities and laboratory studies including:  complete blood picture (CBC), coagulation profile, D-Dimer, serum biochemical tests including cardiac biomarkers and ferritin, rapid test  or PCR, computed tomography (CT), ECG results and echocardiography results if found. We intended to find the association among  COVID-19 and STEMI outcomes on patient presented to Emergency Department at Suez Canal University.

Results: In-hospital mortality  rates were 34.04% for patients with STEMI along with COVID-19 compared to 4.3% for those with STEMI without COVID-19. COVID 19  patients had leukocytosis and lymphocytopeni. Moreover, COVID 19 patients had elevated d-dimer, TLC and CRP.

Conclusion: When  compared to patients who were not diagnosed with COVID-19, individuals with STEMI had significantly greater rates of in-hospital  mortality when they also had a concurrent out-of-hospital or in-hospital COVID-19 infection.