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Role of nanoparticles in diagnosis and management of parasitic diseases: Review article


Maha Talaat Elhefny
Nahed E. Mostafa
Eman Aly Mohamed
Reda M. Abdelhameed
Mohamed Hassan Sarhan
Howayda Said Fouad Moawad

Abstract

Background: An extensive class of materials, nanoparticles (NPs) include particulate compounds with a minimum diameter of 100 nanometers (nm). This is because of their tiny size and huge surface area, which allows them to traverse the blood-brain barrier, enter the respiratory system and be adsorbable through endothelial cells. Today, nanoparticles for drug administration are being studied to increase their sustained release, intracellular penetrability as well as bioavailability, due to the constant development and innovation of nanomedicine.
Objective: To determine how nanoparticles can help diagnose and treat parasitic diseases.
Conclusion: Nanoparticles could be conjugated with proteins and immunoglobulins that could help in specific diagnosis of several parasitic diseases, in addition, improved efficacy and reduced harmful side effects can be achieved by immobilizing antiparasitic medicines on or inside nanomaterials.


Journal Identifiers


eISSN: 2090-7125
print ISSN: 1687-2002