Effect Of Green Leaves And Germination And Boiling Treatments Of Fenugreek And Lupin Seeds On Chemical Composition, Serum Glucose, Lipid Profile And Hepatic Enzymes Of Rats

Abstract

Raw, boiled and germinated fenugreek seeds of three kinds of fenugreek (Trigonella foenum graecum L.) were commercial, Giza 2 and Giza 30 and fenugreek green leaves and raw, boiled and germinated commercial sweet lupin seeds (lupinus termis forssk L.) were analyzed for its chemical composition, alkaloids and antioxidant activity. Essential fatty acids of fenugreek seed oil were also determined. Prophylactic effect of all treatments of the best kind of two legumes (commercial fenugreek and lupin seeds) in addition to fenugreek green leaves on serum glucose, lipid profile and liver enzymes of rats fed hyperlipidemic diet were studied. Also liver tissues of rats were histopathologically examined. The recorded analysis showed slight differences in chemical composition of treated seeds. However, commercial fenugreek seed oil was the best in fatty acids. Also commercial fenugreek and lupin seeds were the best in antioxidant components and activity especially germinated seeds. Germinated and boiled fenugreek seeds and fenugreek leaves and germinated lupin seeds reduced the increases of serum glucose, total cholesterol, triglycerides, LDL, VLDL risk ratio and hepatic enzymes ALT and AST and increased HDL and avoid the damage in liver tissues resulted from hyperlipidemic diet effect compared to positive control.

Egyptian Journal of Biomedical Sciences Vol. 23 (1) 2007: pp. 39-59