Effect of Cymbopogon ctratus L. essential oil on the growth and morphogenesis of Candida albicans

Abstract

Addition of 2.0 l/ml of Cymbopogon citratus L. essential oil to the Sabouraud\'s medium was inhibited growth completely of Candida albicans in liquid medium. Light microscope and scanning electron microscope observation showed morphogenic changes in the treated cells including decrease in cell size. While investigation by transmission electron microscope also showed changes in the ultrastructure of cells including: cell wall, plasma membrane and mitochondria. Oil treatment also increased leakage of ions from yeast cells and decreased in its lipid content.

Egyptian Journal of Biotechnology Vol. 25 (1) 2007: pp. 145-158